Februar 08, 2019
Syringes Drug Delivery Packaging Pharmapack 2019

First Glass Pre-Fillable Syringe Validated for Delivery of Intravenous Drugs

BD (Becton, Dickinson and Company), a leading global medical technology company, presented BD HylokTM, its new glass pre-fillable syringe for the administration of viscous solutions such as hyaluronic acid dermal fillers, at Europe's dedicated pharmaceutical packaging and drug delivery event, Pharmapack 2019, from February 6 to 7 in Paris, France.

Injection of hyaluronic acid exerts a high pressure on the syringe, due to the product’s viscosity.(1) This high pressure may cause needle disconnection and syringe luer-lok adaptor (LLA) rotation, which may lead to leakage. A recent international survey found that 45 percent of dermatologists identified leakage as the main problem with hyaluronic acid syringes.(2) High viscosity solutions have traditionally been administered by dermatologists using both glass and plastic syringes. Glass syringes are preferred by product manufacturers for their inertness and durability.(3)

BD Hylok is also the first glass pre-fillable syringe that is validated for delivery of intravenous drugs.4 It is compatible with main IV connectors and can be used for various indications where time, precision and dependability are essential.(5)

BD Hylok LLA is strongly affixed, using new bonding technology, and reduces the risk of LLA rotation or disconnection. Its LLA thread design provides a safe and robust needle and IV connection with needle as well as with IV connectors.

Peter Nolan, Worldwide President of BD Pharmaceutical Systems, said: “Our expanded portfolio of solutions on display during this year’s Pharmapack event, including the recent launch of BD Hylok, exemplifies BD’s ability to continuously innovate. By offering a stronger and better connection with needles and IV connectors, this new syringe has an array of medical uses and benefits that will suit multiple needs across the healthcare and medical aesthetics markets.”

BD Hylok is available in 1ml long format and additional sizes will be introduced in the future. BD Hylok comes with an extensive data package, to support product or drug manufacturers developmental, technical and registration efforts.

At Pharmapack’s Innovation Gallery, an exhibition which showcases the most innovative products from the pharmaceutical packaging and drug delivery industry, BD presented novel products including BD Hylok and BD Intevia, a uniquely designed disposable autoinjector for high-viscous drug delivery.

More than 70 percent of the top 100 global pharmaceutical companies use BD Medical-Pharmaceutical Systems’ pre-fillable drug-delivery systems for a variety of therapeutic applications.(6) With an extensive portfolio of pre-fillable syringes, self-injection systems, safety and shielding solutions, BD’s products are designed to protect, package and deliver drug therapies, and to maximize healthcare worker and patient safety.

For more information on BD Hylok please visit BD's website.

MTME Trade Show Zone for Pharmapack 2019

1. Monheit and Coleman, 2016, “Hyaluronic acid fillers”. Dermatologic therapy,19(3), 141-150.
2. Voice of Customer research, The MarketTech Group. February 2018. N = 87 dermatologists (US, EU, Asia).
3. Voice of Customer research, The MarketTech Group. November 2017. N = 36 including managers in manufacturing, quality, R&D, procurement, marketing & sales, general management (EU, Asia).
4. BD HylokTM Human Factor study [internal report] – Pont-de-Claix, FR: Becton Dickinson and Company; 2017.
5. BD HylokTM IV connectors and needles compatibility [Internal Report]. Pont-de-Claix, Becton Dickinson and Company, 2016.
6. IQVIA-based analysis & BD Internal systems (SAP ECC, SAP Legacy, Tracis, Nodum) – 2016 update

Source: BD - Becton, Dickinson and Company